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      5-Star Hotels in Santa Cruz de la Sierra

      Compare 3 top-rated 5-star hotels in Santa Cruz de la Sierra with pools, spas, and airport shuttles. Exclusive deals available. Check rates now.

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      Wed, 10 Jun
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      Thu, 11 Jun
      Rooms and Guests2 Guests, 1 room
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      Rooms and Guests2 Guests, 1 room
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      Check-in
      Wed, 10 Jun
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      Rooms and Guests2 Guests, 1 room
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      1-3 out of 3
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      Hotel Camino RealHotel
      8.8
      Great705 total reviews
      our site & Booking.com
      Located in the business district of Santa Cruz de La Sierra, within 8 minutes' walk of Fidalga, the 5-star family-friendly Camino Real offers access to a hot tub, massage facilities and an outdoor swimming pool.
      FromUS$ 94 /nightSelect
      Marriott Santa Cruz De La Sierra HotelHotel
      9.0
      Perfect378 total reviews
      our site & Booking.com
      Map
      2.5 mi from City Center1.1 mi from Consulate of Brazil
      El Cristo is around 1.4 miles from the 5-star Marriott Santa Cruz de La Sierra, while Parque El Arenal is approximately 1.8 miles away.
      FromUS$ 96 /nightSelect
      Radisson Hotel Santa CruzHotel
      7.8
      Very good93 total reviews
      our site & Booking.com
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      3.6 mi from City Center
      Boasting a steam room, a hot tub and sauna facilities, the 5-star luxury Radisson Hotel Santa Cruz Santa Cruz de La Sierra is available in a business area.
      FromUS$ 95 /nightSelect

      Most five-star hotels in Santa Cruz de la Sierra cluster near the business district and the international airport. Expect nightly rates starting around $150 for rooms with modern furnishings, cable TV, and air conditioning. Many properties offer airport shuttles, multiple outdoor pools, and full-service spas to unwind after a day of meetings or sightseeing.

      The Hotel Camino Real stands out with two swimming pools, a water slide, and a spa featuring a sauna and hot tub, making it a top choice for families and business travelers. The Radisson Hotel Santa Cruz caters to airport transit and golf enthusiasts, while the Marriott Santa Cruz De La Sierra Hotel delivers a luxury design-oriented stay with premium spa amenities.