5-Star Hotels in Santa Cruz de la Sierra

Book top 5-star hotels in Santa Cruz de la Sierra now. Compare 3 top-rated hotels near downtown with pools, spas & exclusive deals. Check rates today.

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Rooms and Guests2 Guests, 1 room
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Rooms and Guests2 Guests, 1 room
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Sun, 23 Aug
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Check-out
Mon, 24 Aug
Rooms and Guests2 Guests, 1 room
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8.8
Great661 total reviews
our site & Booking.com
Indoor PoolGiant WaterslideMeeting Venues
  • Indoor pool and outdoor waterslide
  • Across from Bolivia's largest mall
  • Nine venues for corporate events
FromUS$ 94 /nightSelect
8.9
Great639 total reviews
our site & Booking.com
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2.1 mi from City Center1232 yd from Consulate of Brazil
Convention CenterOutdoor PoolFull Spa
  • Largest hotel convention center in Bolivia
  • Tropical oasis with lush gardens
  • Exclusive Club Lounge perks
FromUS$ 116 /nightSelect
9.0
Perfect378 total reviews
our site & Booking.com
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2.5 mi from City Center1.1 mi from Consulate of Brazil
Full-Service SpaOutdoor PoolBusiness Center
  • 2021 TripAdvisor Travelers Choice
  • Highest ceilings & advanced AV
  • On-site Japanese sushi bar
FromUS$ 96 /nightSelect
7.8
Very good93 total reviews
our site & Booking.com
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3.6 mi from City Center
Infinity PoolMini GolfSpa
  • Infinity pool with scenic views
  • Themed dinners and culinary experiences
  • On-site mini golf for families
FromUS$ 95 /nightSelect
8.8
Great1126 total reviews
our site & Booking.com
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1300 yd from City Center282 yd from Sacred Art Museum
Outdoor PoolOn-site SpaAirport Shuttle
  • Open-air design with natural light
  • 50m from Art Museum of Central Bank
  • Free full breakfast and WiFi
FromUS$ 71 /nightSelect

Santa Cruz de la Sierra offers a selection of high-end hotels for travelers seeking premium accommodations. Budget for a stay in the city typically starts around $100 to $250 per night, depending on the season and property. The best districts to look for top-tier hotels include the business and commercial areas near downtown, such as the Equipetrol neighborhood, where many luxury properties are concentrated. These hotels cater to both business and leisure guests with facilities like full-service spas, multiple pools, and on-site fine dining.

Top-rated options in the city include Hotel Camino Real, which earns an 88/100 guest rating and features two swimming pools, a full spa with sauna and hot tub, plus a children's playground. Marriott Santa Cruz de la Sierra is another standout, scoring 90/100 and appealing to design-conscious travelers and spa enthusiasts. Radisson Hotel Santa Cruz offers a more family-friendly atmosphere with airport proximity. For a focused selection, check out these three 5-star hotels in Santa Cruz de la Sierra.