Downtown Buffalo Vacations: Best Hotels in the City Center

Compare 17 downtown Buffalo hotels near Niagara Square, Shea's, and KeyBank Center. Find deals on top-rated stays with free WiFi, pools, and on-site dining. Check rates now.

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1-17 out of 17
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  • Price: high to low
  • Guest rating: high to low
  • Popularity: high to low
8.4
Great120 total reviews
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153 yd from City Center284 yd from Buffalo Niagara Convention Center
Hot Springs PoolRotating BarRooftop Lounge
  • Year-round hot springs pool
  • Only revolving bar in Buffalo
  • Rooftop bar with city skyline views
FromUS$ 329 /nightSelect
7.6
Very good900 total reviews
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83 yd from City Center256 yd from Buffalo Niagara Convention Center
Rooftop PoolFull-Service SpaBusiness Center
  • Convention center connected
  • Historic 1923 Genesee Building
  • Rooftop pool with city views
FromUS$ 108 /nightSelect
8.6
Great99 total reviews
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356 yd from City Center344 yd from Shea's Performing Arts Center
Patina RestaurantFitness StudioBusiness Center
  • Robot room delivery service
  • Local artist-inspired decor
  • State-of-the-art gym views
FromUS$ 844 /nightSelect
9.3
Perfect197 total reviews
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1502 yd from City Center209 yd from Canalside Buffalo
M Club LoungePanorama RestaurantTim Hortons
  • Direct link to KeyBank Center
  • M Club premium lounge
  • Waterfront dining at Panorama
FromUS$ 174 /nightSelect
7.5
Very good92 total reviews
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489 yd from City Center186 yd from Shea's Performing Arts Center
24-Hour BarSaltwater PoolFitness Center
  • 24-hour bar with live music
  • In-room Bliss Spa amenities
  • Saltwater indoor pool
FromUS$ 199 /nightSelect
8.1
Great593 total reviews
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335 yd from City Center356 yd from Buffalo Niagara Convention Center
Indoor PoolItalian RestaurantFitness Center
  • Complimentary made-to-order breakfast
  • Spacious two-room corner suites
  • Historic Avant building architecture
FromUS$ 155 /nightSelect
6.5
Nice390 total reviews
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502 yd from City Center146 yd from Main Place Mall
Fitness CenterMeeting RoomsOnsite Brewpub
  • Individually styled historic rooms
  • Onsite brewpub with brunch
  • Minutes walk to Shea's Theater
FromUS$ 128 /nightSelect
9.1
Perfect177 total reviews
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794 yd from City Center512 yd from Shea's Performing Arts Center
Butler ServiceOn-site SpaPrivate Dining
  • Certified butler for each guest
  • Historic Victorian mansion charm
  • Complimentary chauffeur service
FromUS$ 219 /nightSelect
8.5
Great594 total reviews
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1574 yd from City Center799 yd from Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site
Valet ParkingShuttle ServiceMeeting Rooms
  • Direct indoor access to hospitals
  • Complimentary shuttle to downtown
  • On-site restaurant with local cuisine
FromUS$ 129 /nightSelect
7.3
Very good1149 total reviews
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1571 yd from City Center120 yd from Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site
Lenox GrillBeer BarBanquet Rooms
  • Oldest continuously operating hotel since 1896
  • Award-winning Lenox Grill restaurant
  • 500+ bottled beers at hotel bar
FromUS$ 115 /nightSelect
8.5
Great613 total reviews
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344 yd from City Center411 yd from Shea's Performing Arts Center
Indoor PoolHot TubConvenience Store
  • Historic Jackson Building hotel
  • Jacuzzi tubs in select rooms
  • Walk to Shea's Theatre events
FromUS$ 186 /nightSelect
8.6
Great276 total reviews
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1359 yd from City Center217 yd from Buffalo, NY Station
Saltwater PoolHot TubBistro
  • Indoor saltwater pool and hot tub
  • Pet-friendly policy up to 75 lbs
  • On-site bistro with Starbucks coffee
FromUS$ 159 /nightSelect
7.8
Very good847 total reviews
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189 yd from City Center165 yd from Shea's Performing Arts Center
Free TrolleyTGI FridaysBusiness Center
  • Free trolley to Canalside
  • On-site TGI Fridays
  • Pancake-making machine
FromUS$ 148 /nightSelect
8.0
Great556 total reviews
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356 yd from City Center85 yd from Lafayette Square
Saltwater PoolGarden GrilleMeeting Rooms
  • Indoor heated saltwater pool
  • On-site Garden Grille & Bar
  • Meeting space for 140 guests
FromUS$ 139 /nightSelect
8.4
Great939 total reviews
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1119 yd from City Center416 yd from Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site
Free ParkingFitness CenterBusiness Center
  • Heart of theater restaurant district
  • Complimentary parking for guests
  • Business rooms with oversized desks
FromUS$ 128 /nightSelect
8.7
Great191 total reviews
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1478 yd from City Center69 yd from Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site
Saltwater PoolFitness CenterShuttle Service
  • Free shuttle to airport and attractions
  • Full kitchens in all suites
  • Gourmet dining with local favorites
FromUS$ 118 /nightSelect
Buffalo Harmony HouseBed & Breakfast
9.4
Perfect130 total reviews
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1592 yd from City Center446 yd from Karpeles Manuscript Library Museum
Hot tubGame roomOutdoor fireplace
  • Historic B&B with garden retreat
  • Customized breakfast for dietary needs
  • Onsite billiards, darts, game room
FromUS$ 298 /nightSelect

For a downtown Buffalo vacation, the city center offers a concentrated mix of historic architecture, major medical campuses, sports venues, and cultural venues. Most hotels here cater to both business and leisure travelers, with budgets ranging from $100 to $250 per night. Key districts to stay include the Niagara Square area (near City Hall) and the Buffalo Niagara Medical Campus, which puts you close to Shea's Performing Arts Center and KeyBank Center. Common amenities across these hotels include free WiFi, on-site fitness centers, and either an indoor pool or a bar and restaurant.

Top-rated properties like Buffalo Marriott at LECOM HARBORCENTER (score 94) offer lake-view rooms and direct access to HarborCenter, while The Westin Buffalo (score 86) places you 400 meters from Shea's Performing Arts Center. For a mix of historic character and modern comfort, Curtiss Hotel (an Ascend Collection property) provides a boutique spa experience with a central location. If you're on a tighter budget, Hotel at the Lafayette (Trademark Collection by Wyndham) sits minutes from Sahlen Field with basic but clean rooms. The Mansion on Delaware Avenue (score 90) offers a quieter, refined stay in a restored historic home.