Charleston's design hotel scene blends historic architecture with contemporary flair. Expect exposed brick, curated art collections, and interiors that nod to the city's past-think antique furnishings, bold prints, and local craftsmanship. These properties are not just places to sleep; they're immersive experiences in neighborhoods like the French Quarter, Marion Square, and Mount Pleasant.
For a design-forward stay, budget around $250-$500 per night, though rates vary seasonally. Top picks include Wentworth Mansion, a 19th-century landmark with a spa, free parking, and in-room breakfast; The Vendue, which doubles as an art gallery with rotating exhibitions; and Hotel Bella Grace, offering kitchenette suites near Marion Square. For a coastal twist, Cambria Hotel Mount Pleasant provides direct beach access, an outdoor pool, and a fitness center-all just a short drive from downtown.